NFL Sunday Betting Previews

Sunday October 18 2026 

Houston Texans at Jacksonville Jaguars

9:30 AM ET | NFL Network | Wembley Stadium, London | Jacksonville -2.5 | Total 42.5

Records: Houston 1-4 SU, 1-4 ATS, 2-3 O/U; Jacksonville 4-1 SU, 3-2 ATS, 1-4 O/U.

Last 3 Houston:
Oct 11 at TEN: SU W 26-3 | ATS W (-6.5)
Oct 4 vs DAL: SU L 30-34 | ATS L (-2.5)
Sep 27 at IND: SU L 17-19 | ATS L (-1.5)

Last 3 Jacksonville:
Oct 11 vs PHI (London): SU W 19-17 | ATS L (-8.5)
Oct 4 at CIN: SU W 22-17 | ATS W (+2.5)
Sep 27 vs NE: SU W 35-6 | ATS W (-2.5) 

2025 matchup: The teams split in 2025: Jacksonville won 17-10 September 21, covering -1.5 (Under 43.5); Houston won 36-29 November 9, covering -1.5 (Over 37.5).

Last game recap: Houston won 26-3 at Tennessee October 11. C.J. Stroud completed 26 of 34 for 261 yards and a touchdown without an interception. Jacksonville beat Philadelphia 19-17 in London, with Trevor Lawrence throwing for 331 yards and two touchdowns against one interception. A late kick return set up Cam Little’s winning 57-yard field goal. Jacksonville stays overseas but moves from Tottenham to Wembley.

QB matchup: C.J. Stroud: 64.3%, 1,402 passing yards, 6 TD/0 INT, 98.1 rating. Trevor Lawrence: 67.1%, 1,174 yards, 10 TD/3 INT, 106.8 rating.

Offense/Defense

Latest key injuries: Houston Friday: Tank Dell (WR, knee), David Montgomery (RB, groin) and Jalen Pitre (S, shoulder) OUT. Henry To’oTo’o (LB, shoulder) and Ja’Marcus Ingram (S, elbow) QUESTIONABLE despite full practice.  Jacksonville Friday: Montaric Brown (CB, hamstring) and Ross Matiscik (LS, shoulder) OUT; Eric Murray (S, concussion) expected back.  Anton Harrison (LT, knee) was placed on IR earlier in the week. 

Weather: Around 54-55°F near the 2:30 PM London kickoff, with some sunshine and a chance of showers later in the game. Neutral field; Jacksonville is the designated home team. 

ATS and totals trends: Houston: 1-5 ATS in its last six overall; Under in four of its last five as an underdog. Jacksonville: four straight Unders; 8-2 Under after an ATS loss.  

Chicago Bears at Atlanta Falcons

1:00 PM ET | FOX | Mercedes-Benz Stadium | Chicago -1.5 | Total 51.5

Records: Chicago 3-2 SU, 3-2 ATS, 1-4 O/U; Atlanta 2-3 SU, 2-3 ATS, 3-2 O/U.

Last 3 Chicago:
Oct 11 at GB: SU L 7-31 | ATS L (-1.5)
Oct 4 vs NYJ: SU W 23-12 | ATS W (-3.5)
Sep 28 vs PHI: SU W 27-7 | ATS W (+3.5)

Last 3 Atlanta:
Oct 11 vs BAL: SU L 23-30 | ATS L (-3.5)
Oct 5 at NO: SU W 45-24 | ATS W (+1.5)
Sep 24 at GB: SU W 35-14 | ATS W (+4.5)

Last game recap: Chicago lost 31-7 at Green Bay October 11. Tyson Bagent and Case Keenum combined for three interceptions; the Bears committed five total turnovers and produced 246 yards. Atlanta lost 30-23 in overtime to Baltimore. Michael Penix Jr. went 19 of 32 for 240 yards and a touchdown before leaving with a rib injury.

QB matchup: Projected Caleb Williams vs. Michael Penix Jr. Williams: 65.5%, 407 yards, 2 TD/1 INT, 92.0 rating in his limited season work. Penix: 67.5%, 719 yards, 3 TD/1 INT, 104.8 rating. Williams practiced fully Wednesday and Thursday after missing three starts; that improves his outlook but is not a final clearance. Atlanta confirms Penix will start. [4,5]

Offense/Defense

Latest key injuries: Chicago latest accessible practice report, Thursday: Kyle Monangai (RB, thumb/toe), T.J. Edwards (LB, hamstring), Keyshaun Elliott (LB, quadriceps) and Dayo Odeyingbo (DE, quadriceps) DNP; Tyrique Stevenson (CB, hip) limited. Williams (QB, hamstring) and Kyler Gordon (CB, calf) full. Gordon still requires an activation check. Atlanta Friday: C.J. Henderson (CB, groin) OUT; Za’Darius Smith (DE, neck) QUESTIONABLE after clearing concussion protocol. Penix (ribs) full/no designation. Drake London (WR, hip), Jake Matthews (LT, groin) and Divine Deablo (LB, hamstring) limited Friday but not on the game-status list.  

Weather: Retractable roof.  

ATS and totals trends: Chicago: 6-0-1 ATS after an ATS loss; 5-1 ATS after a SU loss. Atlanta: 1-6 ATS in its last seven home games; 0-4 ATS after allowing more than 150 rushing yards. Chicago is 1-4 O/U this season despite the relatively high total.

Baltimore Ravens at Cleveland Browns

1:00 PM ET | FOX | Huntington Bank Field | Baltimore -3 to -3.5 | Total 39.5-40.5 

Records: Baltimore 4-1 SU, 2-3 ATS, 3-2 O/U; Cleveland 3-2 SU, 3-2 ATS, 3-2 O/U.

Last 3
Baltimore: Oct 11 at ATL: SU W 30-23 | ATS W (+3.5)
Oct 4 vs TEN: SU W 24-18 | ATS L (-11.5)
Sep 27 at DAL: SU W 34-31 | ATS L (-3.5)

Last 3 Cleveland:
Oct 11 at NYJ: SU L 12-17 | ATS L (+2.5)
Oct 1 vs PIT: SU W 27-24 | ATS W (+2.5)
Sep 27 vs CAR: SU W 21-18 | ATS W (+2.5) 

2025 matchup: Baltimore swept in 2025: 41-17 September 14, covering -12.5 (Over 46.5), and 23-16 November 16, with Cleveland covering +7.5 (Over 37.5).

Last game recap: Baltimore won 30-23 in overtime at Atlanta October 11. Tyler Huntley completed 24 of 32 for 201 yards and two touchdowns without an interception, then scored the winning rushing touchdown. Cleveland lost 17-12 at the Jets. Deshaun Watson went 15 of 33 for 155 yards and a touchdown but took eight sacks.

QB matchup: Tyler Huntley vs. Deshaun Watson. Huntley: 264 passing yards, 2 TD/0 INT, 109.8 rating in limited work; latest 201 yards, 2 TD/0 INT. Watson: 64.2%, 1,010 yards, 7 TD/2 INT, 94.1 rating. Lamar Jackson is ruled out, so his 119.6 season rating should not be used as this game’s active QB comparison.

Offense/Defense

Latest key injuries: Baltimore Friday: Lamar Jackson (QB, ankle), Cam Jurgens (C, concussion) and Matt Hibner (TE, hand) OUT. Rashod Bateman (WR, shoulder) returned in a non-contact jersey; Zay Flowers (WR, toe) and Mike Green (EDGE, hamstring) were on the field. Their participation is not a final availability guarantee. Cleveland Friday: Quinshon Judkins (RB, ankle), Mason Graham (DT, knee/ankle), Carson Schwesinger (LB, ankle) and Derek Barnett (DE, ankle) returned to practice. Mike Hall Jr. (DT, ankle), Teven Jenkins (G, back) and Kalia Davis (DT, quadriceps) remained absent. Tytus Howard (OT, knee) improved to limited Thursday; Dylan Sampson (RB, knee) also returned to limited work. 

Weather: Sunny, about 58°F at kickoff, warming into the low 60s. 

ATS and totals trends: Baltimore: 1-4 ATS after an ATS win. Cleveland: four straight home ATS wins; 5-1 ATS in its last six AFC games; 6-1 Over after an ATS loss. Five straight series meetings went Over, but Cleveland also carries a 5-1 Under run as an underdog.

Tennessee Titans at Indianapolis Colts

1:00 PM ET | FOX | Lucas Oil Stadium | Indianapolis -6.5 to -7 | Total 44.5 

Records: Tennessee 0-5 SU, 2-3 ATS, 1-4 O/U; Indianapolis 2-3 SU, 3-2 ATS, 3-2 O/U.

Last 3 Tennessee:
Oct 11 vs HOU: SU L 3-26 | ATS L (+6.5)
Oct 4 at BAL: SU L 18-24 | ATS W (+11.5)
Sep 27 at NYG: SU L 7-12 | ATS L (+2.5)

Last 3 Indianapolis:
Oct 11 at PIT: SU L 22-34 | ATS L (+2.5)
Oct 4 at WAS: SU W 30-13 | ATS W (-5.5)
Sep 27 vs HOU: SU W 19-17 | ATS W (+1.5) [30]

2025 matchup: Indianapolis swept in 2025: 41-20 September 21, covering -5.5 (Over 42.5), and 38-14 October 26, covering -14.5 (Over 47.5).

Last game recap: Tennessee lost 26-3 at home to Houston October 11. Cam Ward completed 23 of 36 for 170 yards, no touchdowns and one interception. The Titans have exceeded 20 points only once. Indianapolis lost 34-22 at Pittsburgh; Daniel Jones went 24 of 44 for 267 yards without a touchdown or interception.

QB matchup: Cam Ward: 63.2%, 896 yards, 3 TD/3 INT, 77.2 rating. Daniel Jones: 61.4%, 1,021 yards, 3 TD/4 INT, 73.6 rating. Both need more touchdowns and fewer possessions disrupted by negative plays.

Offense/Defense

Latest key injuries: Tennessee Friday: Kevin Winston Jr. (S, quadriceps) OUT. Amani Hooker (S, concussion) was expected to return, pending the final independent evaluation. Tyjae Spears (RB, knee) returned to practice after a Thursday DNP; Marcus Harris (CB, ankle) and David Martin-Robinson (TE, hamstring) also practiced. Joshua Williams (CB, pectoral) remains an activation decision. Indianapolis: Ashton Dulin (WR, hamstring) and Jaylon Carlies (LB, ribs) ruled OUT Friday. Daniel Jones (QB, ankle), Josh Downs (WR, hamstring/rest) and Will Mallory (TE, thumb) were full Thursday; Jalen Travis (OT, ankle) improved to limited.

Weather: Retractable-roof stadium.  

ATS and totals trends: Tennessee: 5-1 ATS after scoring fewer than 15 points; Under in four of five this season; four straight road Overs. Indianapolis: 4-1 Over in its last five AFC games. The favorite is 4-1 ATS in the last five series meetings.

New York Jets at New England Patriots

1:00 PM ET | CBS | Gillette Stadium | New England -7.5 | Total 43.5 

Records: Jets 2-3 SU, 3-2 ATS, 1-4 O/U; New England 3-2 SU, 4-1 ATS, 2-3 O/U.

Last 3 Jets:
Oct 11 vs CLE: SU W 17-12 | ATS W (-2.5)
Oct 4 at CHI: SU L 12-23 | ATS L (+3.5)
Sep 27 at DET: SU L 24-31 | ATS L (+6.5)

Last 3 New England:
Oct 11 vs LV: SU W 45-17 | ATS W (-3.5)
Oct 4 at BUF: SU W 29-26 | ATS W (+7.5)
Sep 27 at JAC: SU L 6-35 | ATS L (+2.5) [31]

2025 matchup: New England swept in 2025: 27-14 November 13, covering -12.5 (Under 42.5), and 42-10 December 28, covering -13.5 (Over 42.5).

Last game recap: The Jets beat Cleveland 17-12 October 11. Geno Smith threw for 182 yards and a touchdown without an interception; Braelon Allen ran for 116 yards and the deciding score. New England beat Las Vegas 45-17. Drake Maye completed 26 of 34 for 374 yards and four passing touchdowns without a pick.

QB matchup: Geno Smith: 69.4%, 1,084 yards, 6 TD/0 INT, 104.2 rating. Drake Maye: 65.6%, 1,228 yards, 8 TD/7 INT, 88.9 rating. Smith’s ball security is a useful counterweight to Maye’s more productive latest game.

Offense/Defense

Latest key injuries: Jets Friday: Breece Hall (RB, quadriceps), Adonai Mitchell (WR, finger), Dylan Parham (G, knee) and Joseph Ossai (EDGE, ankle) OUT, per Aaron Glenn. Latest accessible practice listing had Kenyon Sadiq (TE, concussion), Omar Cooper Jr. (WR, ankle) and Dane Belton (S, knee) limited; Sadiq requires protocol clearance and Cooper an activation check. Patriots Thursday: Carlton Davis III (CB, neck) DNP; A.J. Brown (WR, ankle), TreVeyon Henderson (RB, ankle), Will Campbell (OT, knee), Morgan Moses (OT, foot) and Marcus Jones (CB, ankle) limited. Drake Maye (QB, right shoulder) and Christian Gonzalez (CB, shoulder) full. 

Weather: Sunny, about 52°F at kickoff and rising into the mid-50s. 

ATS and totals trends: Jets: Under in four of five this season. New England: 7-0 ATS as a home favorite; 8-1 ATS in its last nine AFC East games; 4-0 Over in its last four divisional games. Those shorter situational runs are context, not stand-alone systems.

New Orleans Saints at New York Giants

1:00 PM ET | FOX | MetLife Stadium | New Orleans -1.5 | Total 45.5 

Records: New Orleans 1-4 SU, 2-3 ATS, 3-2 O/U; Giants 3-1-1 SU, 4-1 ATS, 3-2 O/U.

Last 3 New Orleans:
Oct 11 vs MIN: SU L 13-23 | ATS L (+2.5)
Oct 5 vs ATL: SU L 24-45 | ATS L (-1.5)
Sep 27 vs LV: SU L 27-35 | ATS L (-4.5)

Last 3 Giants:
Oct 11 at WAS: SU T 27-27 | ATS W (+3.5)
Oct 4 vs ARI: SU W 36-24 | ATS W (+2.5)
Sep 27 vs TEN: SU W 12-7 | ATS W (-2.5) [32]

2025 matchup: New Orleans won 26-14 October 5, 2025, covering -1.5; the game stayed Under 41.5.

Last game recap: New Orleans lost 23-13 to Minnesota October 11. Tyler Shough completed 16 of 25 for only 96 yards, with no touchdowns and two interceptions. The Giants tied Washington 27-27 after erasing a 14-point fourth-quarter deficit. Jameis Winston threw for 326 yards and three touchdowns without an interception.

QB matchup: Tyler Shough: 66.8%, 1,299 yards, 9 TD/5 INT, 88.6 rating. Jameis Winston: 57.6%, 805 yards, 6 TD/3 INT, 81.2 rating. Winston remains the current starter following Jaxson Dart’s knee injury; last week’s success does not erase his lower season completion rate.

Offense/Defense

Latest key injuries: Saints Friday: Kaden Elliss (LB, calf) and Anfernee Jennings (EDGE, knee) OUT. Alvin Kamara (RB, back), Chris Olave (WR, illness), Nathan Shepherd (DL, illness), Lorenzo Styles Jr. (DB, knee) and Zach Wood (LS, calf) QUESTIONABLE. Olave returned to limited work Friday. Shough (QB, left hand) full/no designation; Jeremiah Wright (G) cleared concussion protocol. Giants latest accessible Thursday report: Andrew Thomas (LT, groin), Jermaine Eluemunor (OT, calf), Abdul Carter (EDGE, calf), Colton Hood (CB, concussion) and Tyler Nubin (S, neck) DNP; Greg Newsome II (CB, groin) and Theo Johnson (TE, neck) limited. Darnell Mooney (WR, neck) and Jason Pinnock (S, concussion) full. 

Weather: Sunny, about 54°F at kickoff, warming toward 57°F. 

ATS and totals trends: Saints: seven straight road ATS wins; 0-5 ATS in October; 6-1 Under after an ATS loss and 6-1 Under in October. Giants: 4-1 ATS this season; 5-0 Over in their last five October games.

Carolina Panthers at Philadelphia Eagles

1:00 PM ET | CBS | Lincoln Financial Field | Carolina -3.5 | Total 38.5

Records: Carolina 2-2 SU, 2-2 ATS, 2-2 O/U; Philadelphia 2-3 SU, 1-4 ATS, 3-2 O/U.

Last 3 Carolina:
Oct 4 vs DET: SU W 32-26 | ATS W (+4.5)
Sep 27 at CLE: SU L 18-21 | ATS L (-2.5)
Sep 20 at ATL: SU W 34-3 | ATS W (-2.5)

Last 3 Philadelphia:
Oct 11 vs JAX (London): SU L 17-19 | ATS W (+8.5)
Oct 4 vs LAR: SU L 20-24 | ATS L (+3.5)
Sep 28 at CHI: SU L 7-27 | ATS L (-3.5) [33]

Last game recap: Carolina last played October 4, beating Detroit 32-26 before its bye. Bryce Young went 29 of 41 for 329 yards and two touchdowns without a pick. Philadelphia lost 19-17 to Jacksonville in London October 11. Jalen Hurts threw for 220 yards and a touchdown, but the Eagles lost on a late 57-yard field goal and return across the Atlantic without a bye.

QB matchup: Bryce Young vs. Tanner McKee. Young: 62.3%, 1,268 yards, 9 TD/2 INT, 100.0 rating. McKee starts for the injured Hurts. McKee’s published career line entering this opportunity is 61.4%, 597 yards, 5 TD/1 INT; those are career figures, not 2026 season totals. [16,17]

Offense/Defense

Latest key injuries: Philadelphia: Jalen Hurts (QB, calf) OUT. Latest accessible Thursday report: Saquon Barkley (RB, hamstring), Will Shipley (RB, foot), Dontayvion Wicks (WR, hamstring), Jalyx Hunt (EDGE, knee/ankle) and A.J. Epenesa (EDGE, back) DNP. DeVonta Smith (WR, hamstring/toe), Marquise Brown (WR, ankle), Drew Kendall (C, knee) and Jonathan Greenard (EDGE, ankle) limited; Landon Dickerson (G, knee) is in a return window, requiring activation. Carolina Friday: AJ Dillon (RB, ankle) OUT; Monroe Freeling (OT, knee) DOUBTFUL; Damien Lewis (G, elbow), Jaelan Phillips (EDGE, hamstring), Trevor Etienne (RB, ankle), Taylor Moton (OT, lungs/blood clot) and Tershawn Wharton (DT, neck) QUESTIONABLE. Etienne, Moton and Wharton also need activation. Young and Jalen Coker (WR, quadriceps) have no designation. 

Weather: Sunny, about 56°F at kickoff, warming toward 59°F. 

ATS and totals trends:  Philadelphia is 1-4 ATS and has five straight Unders after a SU loss. 

Pittsburgh Steelers at Tampa Bay Buccaneers

1:00 PM ET | CBS | Raymond James Stadium | Pittsburgh -2.5 | Total 38.5

Records: Pittsburgh 3-2 SU, 3-2 ATS, 3-2 O/U; Tampa Bay 1-4 SU, 1-4 ATS, 2-3 O/U.

Last 3 Pittsburgh:
Oct 11 vs IND: SU W 34-22 | ATS W (-2.5)
Oct 1 at CLE: SU L 24-27 | ATS L (-2.5)
Sep 27 vs CIN: SU W 30-27 | ATS W (+3.5)

Last 3 Tampa Bay:
Oct 8 at DAL: SU W 24-16 | ATS W (+9.5)
Oct 4 vs GB: SU L 14-17 | ATS L (+2.5)
Sep 27 vs MIN: SU L 16-23 | ATS L (+1.5) [34]

Last game recap: Pittsburgh beat Indianapolis 34-22 October 11. Aaron Rodgers completed 22 of 31 for 235 yards and three touchdowns without an interception. Tampa Bay earned its first win, 24-16 at Dallas Thursday October 8. Jalon Daniels went 19 of 25 for 189 yards, a touchdown and no pick. Tampa has ten days between games; Pittsburgh has seven.

QB matchup: Aaron Rodgers: 59.8%, 1,234 yards, 10 TD/4 INT, 88.9 rating. Jalon Daniels: 69.1%, 337 yards, 2 TD/3 INT, 74.6 rating. Daniels starts again with Baker Mayfield ruled out; do not confuse Tampa’s Jalon Daniels with Washington’s Jayden Daniels. [19]

Offense/Defense

Latest key injuries: Pittsburgh: Roman Wilson (WR, finger) and Ben Skowronek (WR, calf) ruled OUT, joining Michael Pittman Jr. on IR. Thursday: Rico Dowdle (RB, toe) full; Jalen Ramsey (CB, wrist), Jamel Dean (CB, ankle) and Keeanu Benton (DT, ankle) limited. DeShon Elliott (S, knee) is limited in an IR return window, not yet confirmed active. Tampa Bay: Mayfield (QB, right thumb) OUT. Thursday: Antoine Winfield Jr. (S, rib) DNP; Sean Tucker (RB, quadriceps), SirVocea Dennis (LB, ankle/foot), Benjamin Morrison (CB, quadriceps) and Ayden Garnes (CB, ankle) limited. Chris Godwin (WR, rest) and Tristan Wirfs (OT, knee) full. 

Weather: Mostly cloudy, about 78°F at kickoff, near 80°F later.    

ATS and totals trends: Pittsburgh: 11-1 Under in Week 6 games; 7-1 ATS in Week 6; 4-0 ATS in its last four road meetings in the series. Tampa Bay: six of its last eight home games went Over.

Arizona Cardinals at Los Angeles Rams

4:05 PM ET | FOX | SoFi Stadium | Los Angeles Rams -12.5 | Total 51.5 

Records: Arizona 1-4 SU, 2-3 ATS, 3-2 O/U; Rams 2-3 SU, 2-3 ATS, 3-2 O/U.

Last 3 Arizona:
Oct 11 vs DET: SU L 21-45 | ATS L (+4.5)
Oct 4 at NYG: SU L 24-36 | ATS L (-2.5)
Sep 27 at SF: SU L 30-36 | ATS W (+7.5)

Last 3 Rams:
Oct 12 vs BUF: SU L 34-37 | ATS L (-3.5)
Oct 4 at PHI: SU W 24-20 | ATS W (-3.5)
Sep 27 at DEN: SU L 26-30 | ATS L (-1.5) 

2025 matchup: The Rams won both 2025-season meetings: 45-17 December 7, covering -9.5 (Over 48.5), and 37-20 January 4, 2026, covering -14.5 (Over 49.5).

Last game recap: Arizona lost 45-21 to Detroit October 11. Jacoby Brissett went 29 of 47 for 292 yards, three touchdowns and one interception; Arizona has allowed at least 30 points in three straight games. The Rams lost 37-34 in overtime to Buffalo Monday October 12. Matthew Stafford completed 40 of 54 for 383 yards and three touchdowns without a pick, but an overtime field-goal try was blocked.

QB matchup: Jacoby Brissett: 66.3%, 1,110 yards, 9 TD/5 INT, 85.2 rating. Matthew Stafford: 64.4%, 1,572 yards, 9 TD/6 INT, 88.3 rating. Stafford’s latest clean passing game is encouraging, but his season interception count remains relevant.

Offense/Defense

Latest key injuries: Arizona: Jeremiyah Love (RB, ankle) ruled OUT Friday. Latest accessible Thursday report: Andrew Wingard (S, knee) and Wydett Williams Jr. (S, concussion) DNP; Kitan Crawford (S, ankle) limited in a return window; Devin Duvernay (WR/returner, ribs) limited. Budda Baker (S), Josh Sweat (EDGE) and Isaac Seumalo (G) returned full after rest. Rams Thursday: Davis Allen (TE, foot) DNP; Colby Parkinson (TE, shoulder), Nate Landman (LB, wrist/shoulder), Josh Wallace (CB, shoulder) and Kam Curl (S, ankle) limited. Omar Speights (LB, knee) full.

Weather: SoFi has a roof and open sides. 

ATS and totals trends: Arizona: six straight Overs in October. Rams: 6-0-1 Under in Week 6; 4-0 ATS in Week 6. Arizona’s current 32.4 PPG allowed is more directly relevant than the calendar trends.

Los Angeles Chargers at Kansas City Chiefs

4:25 PM ET | CBS | GEHA Field at Arrowhead Stadium | Kansas City -7.5 to -8.5 | Total 41.5

Records: Chargers 0-5 SU, 0-5 ATS, 1-4 O/U; Kansas City 4-0 SU, 2-2 ATS, 2-2 O/U.

Last 3 Chargers:
Oct 11 vs DEN: SU L 17-23 | ATS L (+3.5)
Oct 4 at SEA: SU L 23-30 | ATS L (+6.5)
Sep 27 at BUF: SU L 16-24 | ATS L (+7.5)

Last 3 Kansas City:
Oct 4 at LV: SU W 30-27 | ATS L (-3.5)
Sep 27 at MIA: SU W 24-10 | ATS W (-9.5)
Sep 20 vs IND: SU W 33-30 | ATS L (-5.5) 

2025 matchup: The Chargers swept in 2025: 27-21 September 5, covering +3 (Over 47.5), and 16-13 December 14, covering +5.5 (Under 41.5).

Last game recap: The Chargers lost 23-17 to Denver October 11. Justin Herbert completed 14 of 24 for 121 yards, one touchdown and an interception; three team turnovers prevented the first win. Kansas City last played October 4, winning 30-27 at Las Vegas before its bye. Patrick Mahomes threw for 225 yards and two touchdowns without an interception.

QB matchup: Justin Herbert: 59.4%, 937 yards, 5 TD/7 INT, 70.2 rating. Patrick Mahomes: 64.1%, 1,037 yards, 9 TD/2 INT, 106.2 rating. Herbert’s protection and receiving support are major variables; Mahomes’ knee listing was accompanied by full practice.

Offense/Defense

Latest key injuries: Latest accessible reports are Thursday participation, not final game designations. Chargers DNP: Joe Alt (OT, neck), Kayode Awosika (G, fibula), Tre’ Harris (WR, hamstring), Donte Jackson (CB, hamstring), Derwin James Jr. (S, hamstring), Bud Dupree (EDGE, neck) and Rodney Shelley (CB, hamstring). Limited: Ladd McConkey (WR, foot), Quentin Johnston (WR, chest), Daiyan Henley (LB, knee), Elijah Molden (DB, hamstring), Dalvin Tomlinson (DL, hamstring) and Brenen Thompson (WR, quadriceps). KeAndre Lambert-Smith (WR, hamstring) is limited in a return window. Chiefs: Rashee Rice (WR, hamstring/knee) DNP; Josh Simmons (OT, back), L’Jarius Sneed (CB, knee) and Peter Woods (DL, neck) limited; Mahomes (QB, knee) full. 

Weather: Sunny, around 65-66°F at the 3:25 PM local kickoff.  

ATS and totals trends: Chargers: 0-5 ATS this season, but 6-1-1 ATS in their last eight visits to Kansas City; seven of their last eight overall went Under. Chiefs: five straight Week 6 Unders; five straight series Unders in Kansas City; 7-0 Under against AFC teams.

Buffalo Bills at Las Vegas Raiders

4:25 PM ET | CBS | Allegiant Stadium | Buffalo -4.5 to -5.5 | Total 53.5 

Records: Buffalo 4-1 SU, 4-1 ATS, 4-1 O/U; Las Vegas 3-2 SU, 4-1 ATS, 3-2 O/U.

Last 3 Buffalo:
Oct 12 at LAR: SU W 37-34 | ATS W (+3.5)
Oct 4 vs NE: SU L 26-29 | ATS L (-7.5)
Sep 27 vs LAC: SU W 24-16 | ATS W (-7.5)

Last 3 Las Vegas:
Oct 11 at NE: SU L 17-45 | ATS L (+3.5)
Oct 4 vs KC: SU L 27-30 | ATS W (+3.5)
Sep 27 at NO: SU W 35-27 | ATS W (+4.5) [37]

Last game recap: Buffalo won 37-34 in overtime at the Rams Monday October 12. Josh Allen threw for 202 yards and a touchdown and ran for 121 yards and another score; James Cook ran for 111 yards and two touchdowns. A blocked Rams field goal kept Buffalo alive before Tyler Bass’ winning kick. Las Vegas lost 45-17 at New England. Kirk Cousins threw for 243 yards and a touchdown without a pick; the defense allowed a huge passing day.

QB matchup: Josh Allen: 65.9%, 1,249 yards, 7 TD/4 INT, 99.6 rating. Kirk Cousins: 65.1%, 1,269 yards, 12 TD/4 INT, 100.7 rating. Fernando Mendoza’s relief appearance last week did not establish a starter change.

Offense/Defense

Latest key injuries: Latest verified team report is Thursday. Buffalo: DJ Moore (WR, shoulder) and Ed Oliver (DT, knee) DNP; Joshua Palmer (WR, shoulder), Dee Alford (CB, ankle), Ty Johnson (RB, hamstring) and T.J. Sanders (DT, shoulder) limited. Spencer Brown (RT, back) improved to full; Christian Benford (CB, toe), Terrel Bernard (LB, knee) and Keon Coleman (WR, ankle) full. Las Vegas: Tonka Hemingway (DT, concussion) DNP; Jalen Nailor (WR, concussion) improved to limited but still needs clearance; Trey Zuhn III (G, knee) limited. Brock Bowers (TE, knee), Ashton Jeanty (RB, foot) and Folorunso Fatukasi (DT, shoulder) full. Carter Runyon (TE, foot) and Dont’e Thornton Jr. (WR, hamstring) are in return windows. 

Weather: Enclosed stadium;

ATS and totals trends: Buffalo: 4-1 ATS and 4-1 Over this season; 7-0-1 Over in its last eight against the Raiders. Las Vegas: 4-1 ATS this season; 5-0 Over against teams with a winning road record. The 53.5 total already reflects a high-scoring expectation.

Dallas Cowboys at Green Bay Packers

8:20 PM ET | NBC / Peacock | Lambeau Field | Green Bay -1.5 | Total 52.5-53.5 

Records: Dallas 2-3 SU, 3-2 ATS, 4-1 O/U; Green Bay 3-2 SU, 2-3 ATS, 2-3 O/U.

Last 3 Dallas:
Oct 8 vs TB: SU L 16-24 | ATS L (-9.5)
Oct 4 at HOU: SU W 34-30 | ATS W (+2.5)
Sep 27 vs BAL: SU L 31-34 | ATS W (+3.5)

Last 3 Green Bay:
Oct 11 vs CHI: SU W 31-7 | ATS W (+1.5)
Oct 4 at TB: SU W 17-14 | ATS W (-2.5)
Sep 24 vs ATL: SU L 14-35 | ATS L (-4.5) [38]

2025 matchup: The September 28, 2025 meeting ended 40-40. Dallas covered +6.5 and the game went Over 46.5.

Last game recap: Dallas lost 24-16 to Tampa Bay Thursday October 8. Dak Prescott went 24 of 42 for 316 yards, a touchdown and two interceptions. Green Bay beat Chicago 31-7 October 11. Jordan Love completed 25 of 31 for 367 yards and two touchdowns without a pick; the defense forced five turnovers and MarShawn Lloyd ran for two scores. Dallas has the longer preparation window.

QB matchup: Dak Prescott: 67.2%, 1,381 yards, 9 TD/3 INT, 97.2 rating. Jordan Love: 60.5%, 1,408 yards, 10 TD/3 INT, 95.5 rating. Love’s latest performance was much cleaner than his season completion rate, while Dallas needs to reduce turnover exposure.

Offense/Defense

Latest key injuries: Dallas: CeeDee Lamb (WR, thigh), Tyler Guyton (LT, back), Tyler Smith (G, thumb) and Shavon Revel Jr. (CB, knee) were full Thursday; Joey Porter Jr. (CB, ankle) also improved to full on the official report. DeMarvion Overshown (LB, hamstring) and Cobie Durant (CB, hamstring) were described Friday as long shots to play; neither should be promoted to confirmed active. Green Bay Friday: Keisean Nixon (CB, groin) practiced and is expected to play barring a setback. Jonathan Ford (DT, calf) will not play, per Matt LaFleur. Javon Hargrave (DT, Achilles), Benjamin St-Juste (CB, hamstring) and Skyy Moore (WR, ankle) remained absent from the observed practice portion. Aaron Banks (G, knee/toe) and Devonte Wyatt (DT, ankle) had been limited. 

Weather: Clear, about 51°F near the 7:20 PM local kickoff, falling into the upper 40s late. 

ATS and totals trends: Dallas: 4-1 Over this season; underdog covered seven straight series meetings; 4-0 Over as a road underdog. Green Bay: five straight Overs after an ATS win; six straight series Overs.