Get ready for a big Sunday and if you need assistance in building your bankroll, ATS is here after 34 years in the business. Check the weather for several potentially rainy games on the East Coast in Baltimore, Carolina, Tampa, and Philadelphia.

Sunday’s NFL Betting Previews

INDIANAPOLIS COLTS (1–2) vs. WASHINGTON COMMANDERS (1–2)
London — 9:30 a.m. ET, NFL Network | Line: Indianapolis -3½ | Total: 48½

Last games: Indianapolis beat Houston 19–17, winning on Spencer Shrader’s 53-yard field goal with 16 seconds remaining. Jones finished 24-of-36 for 235 yards, one touchdown and one interception. Washington upset Seattle 33–31; Mariota went 19-of-31 for 183 yards and three touchdowns without an interception. 

Offense vs. defense: Washington allows 280.3 passing yards per game, but only 82 rushing yards. That makes this a demanding matchup for Jonathan Taylor and places more responsibility on Jones against Washington’s frequent blitzes. Indianapolis allows a league-worst 417.3 total yards per game, including 141.3 rushing yards. Washington has a route to controlling possession through its running game, while Indianapolis needs efficient passes against a vulnerable secondary.  

Key Injuries: 

• Colts: WR Keenan Allen—questionable, groin. WR Alec Pierce remains on IR, reducing receiving depth. Jonathan Taylor and Charvarius Ward returned to full practice Thursday. 
• Commanders: QB Jayden Daniels—out, elbow; Marcus Mariota will start. RB Rachaad White—out, shoulder; G Sam Cosmi—out, concussion; S Nick Cross—out, illness. WR Terry McLaurin—questionable, hamstring.  

Key ATS trend: Washington 4–1 ATS in its last five as an underdog. 

NEW ENGLAND PATRIOTS (1–2) at BUFFALO BILLS (3–0)
1 p.m. ET, CBS | Line: Buffalo -7 | Total: 48½

Last games: New England lost 35–6 at Jacksonville. Maye threw for 199 yards with two interceptions and no touchdowns. Buffalo beat the Chargers 24–16, despite Allen throwing two interceptions and no passing touchdowns. Allen supplied two rushing touchdowns.  

Offense vs. defense: Allen’s 9.1 yards per attempt gives Buffalo a substantial explosive-play advantage. Maye’s six interceptions are New England’s biggest problem, but Buffalo’s defense offers opportunities: it allows 361.3 yards per game, including 254.3 through the air.

2025 meetings: New England won 23–20 at Buffalo, covering +7½. Buffalo won 35–31 at New England, covering -2½. 

• Patriots: CB Christian Gonzalez and DT Christian Barmore—out, shoulder injuries. OT Morgan Moses—questionable, foot; LB Dre’Mont Jones—questionable, shoulder. Drake Maye practiced fully with a right-shoulder issue and carries no game designation. 
• Bills: CB Christian Benford—questionable, toe; RB Ray Davis—questionable, hamstring; DL T.J. Sanders—doubtful, illness. 

ATS Key trend: New England 5–0 ATS in its last five following a straight-up loss.  

NEW YORK JETS (1–2) at CHICAGO BEARS (2–1)
1 p.m. ET, FOX| Line: Chicago -3½ | Total: 43½

Caleb Williams remains sidelined by a hamstring injury. Chicago had not settled publicly on Keenum or Bagent in the reporting reviewed. 

Last games: The Jets lost 31–24 at Detroit, despite Smith completing 31-of-37 passes for 321 yards and three touchdowns. Chicago beat Philadelphia 27–7 Monday; Keenum threw for 247 yards and two touchdowns, added a rushing touchdown, and benefited from three defensive takeaways.

Offense vs. defense: Smith’s accuracy and zero interceptions challenge Chicago’s reliance on takeaways. The Bears allow 6.4 yards per play and 5.1 per rush, but Breece Hall’s quad injury could prevent the Jets from exploiting that rushing weakness. 

2025 meeting: None; the Jets won 31–10 in 2022. 

Key Injuries: 

• Jets: RB Breece Hall—out, quadriceps; WR Adonai Mitchell—out, finger; TE Mason Taylor—out, thumb; G Dylan Parham—out, knee. TE Kenyon Sadiq—questionable, back.  
• Bears: QB Caleb Williams—out, hamstring. RB D’Andre Swift—questionable, knee. OT Braxton Jones—knee injury, missed Wednesday and Thursday; final status pending in the report reviewed.

Key ATS trend: Chicago 7–0 ATS in its last seven after gaining more than 350 yards.

DALLAS COWBOYS (1–2) at HOUSTON TEXANS (0–3)
1 p.m. ET, FOX | Line: Houston -3 | Total: 48½

Last games: Dallas lost 34–31 to Baltimore in Brazil. Prescott finished 25-of-40 for 276 yards, one touchdown and no interceptions. Houston lost 19–17 at Indianapolis on a late field goal; Stroud managed 167 passing yards and one touchdown. Houston has scored just 23 points across its last two games.  

Offense vs. defense: Houston’s run defense allows only 86.7 yards per game and 3.5 per carry, which could push Dallas toward Prescott. The Texans are more vulnerable through the air, allowing 238.7 passing yards per game. My assessment: Dallas has demonstrated better touchdown production at quarterback. Houston needs to turn Stroud’s yardage and ball security into sustained scoring drives, while its defensive front must prevent Prescott from finding a comfortable rhythm. 

2025 meeting: None; Houston won 34–10 at Dallas in 2024, covering -7½.  

• Cowboys: CB Cobie Durant—hamstring, LB DeMarvion Overshown—hamstring, and CB Shavon Revel—knee/ankle missed both Wednesday and Thursday. S Malik Hooker—forearm, limited.  
• Texans: WR Nico Collins—hamstring and G Ed Ingram—groin, limited Thursday. LB Azeez Al-Shaair—groin, did not practice. DE Jadeveon Clowney—knee, limited;  

Key ATS trend: Road team 5–0 ATS in the last five meetings. 

ARIZONA CARDINALS (1–2) at NEW YORK GIANTS (2–1)
1 p.m. ET, CBS| Line: Arizona -2½ | Total: 44½

Winston is expected to continue starting following Jaxson Dart’s season-ending knee injury.

Last games: Arizona lost 36–30 at San Francisco. Brissett completed 38-of-52 passes for 280 yards and two touchdowns without an interception. The Giants beat Tennessee 12–7 without scoring a touchdown; Winston went 14-of-22 for 118 yards. 

Offense vs. defense: Brissett’s completion percentage looks strong, but his low yards per attempt shows Arizona depends heavily on underneath throws. The Cardinals average just 4.7 yards per play. New York’s defense has allowed only 18.3 points per game, while its offense needs substantially more from Winston.  

Key Injuries:

• Cardinals: C Hjalte Froholdt—knee, DT Walter Nolen—shoulder, and DT Roy Lopez—groin, limited Thursday. S Dadrion Taylor-Demerson—back, missed practice. RB James Conner remains on IR with a foot injury.  
• Giants: QB Jaxson Dart—out for the season, knee; EDGE Brian Burns—season-ending knee injury. OT Andrew Thomas—groin, missed consecutive practices. RB Tyrone Tracy Jr.—knee, CB Deonte Banks—calf, and S Tyler Nubin—calf, limited Thursday

Key ATS trend: Arizona 5–0 ATS in the last five meetings.

LOS ANGELES RAMS (1–2) at PHILADELPHIA EAGLES (2–1)
1 p.m. ET, FOX | Line: Los Angeles -3½ | Total: 42½

Last games: The Rams lost 30–26 at Denver. Stafford threw for 390 yards and two touchdowns, but also two interceptions. Philadelphia lost 27–7 at Chicago; Hurts threw for only 153 yards, with one interception and no passing touchdowns. His rushing touchdown supplied Philadelphia’s only score.  

Offense vs. defense: Los Angeles leads the league at 417.7 yards per game, yet has converted only five of 10 red-zone trips into touchdowns. Philadelphia allows 127.3 rushing yards per game, presenting an opportunity for the Rams to establish balance. The Eagles average only 302.3 offensive yards, and their defense has yet to record a takeaway. Philadelphia needs its ground game and Hurts’ mobility to restore offensive efficiency. Turnovers and red-zone execution could outweigh total yardage.  

2025 meeting: Philadelphia won 33–26, covering -3½; the game went Over 45½. The January 2025 playoff meeting belonged to the 2024 season.  

• Rams: DT Aaron Donald—out, back; EDGE Myles Garrett remains on IR following knee surgery. CB Jaylen Watson—out, shoulder; S Kamren Kinchens—out, hamstring. TE Terrance Ferguson is expected to miss the game with an ankle sprain; TE Colby Parkinson—shoulder/knee, availability uncertain. WR Puka Nacua is expected to return from his hip injury.  
• Eagles: WR DeVonta Smith—ruled out, hamstring. TE Dallas Goedert—out, knee. LB Zack Baun—concussion,

Key ATS trend: Philadelphia 6–0 ATS in its last six as an underdog.  

GREEN BAY PACKERS (1–2) at TAMPA BAY BUCCANEERS (0–3)
1 p.m. ET, FOX | Line: Green Bay -3½ | Total: 38½

Mayfield’s dislocated throwing-hand thumb has Tampa Bay preparing rookie Jalon Daniels for a potential first start. Daniels spent six seasons at Kansas, tossing for 9,282 yards with 67 TDs and 31 INTs. He was also a strong runner, who rushed for 404 yards last season and 1,445 yards in his career. Journeyman Brett Rypien was signed to the practice squad and will be the backup with Mayfield out.

Last games: Green Bay lost 35–14 at Atlanta Thursday. Love needed 53 attempts to produce 312 yards, two touchdowns and one interception. Tampa Bay lost 23–16 to Minnesota. Mayfield threw for 217 yards before his injury; Daniels completed none of three relief attempts and threw an interception. 

Offense vs. defense: Green Bay averages a league-low 48.7 rushing yards, while Tampa Bay allows only 76 rushing yards and 3.1 per carry. The quarterback advantage alone does not make this an easy road assignment for Green Bay. Love may need to carry the offense against an effective run defense. Tampa Bay should favor a conservative plan if Daniels starts, but falling behind would force the rookie into a much harder situation. 

2025 meeting: None; Tampa Bay won 34–20 in 2023. 

Key Injuries:

• Packers: G Aaron Banks—knee/toe and C/G Jacob Monk—quadriceps, missed Thursday. LB Edgerrin Cooper—shoulder/concussion and EDGE Lukas Van Ness—shoulder, limited. Final designations pending in the report reviewed. 
• Buccaneers: QB Baker Mayfield—out, dislocated right thumb; rookie Jalon Daniels is set to start. RB Bucky Irving—glute, limited Thursday. WR Chris Godwin—ankle, returned to full practice. EDGE Rueben Bain Jr.—groin/shoulder and LB SirVocea Dennis—calf, missed Thursday.

Key ATS trend: Underdog 4–0 ATS in the last four meetings.  

TENNESSEE TITANS (0–3) at BALTIMORE RAVENS (2–1)
1 p.m. ET, CBS | Line: Baltimore -11½ | Total: 42½

Last games: Tennessee lost 12–7 at the Giants. Ward finished 23-of-36 for 181 yards, one touchdown and one interception. Baltimore beat Dallas 34–31 in Brazil; Jackson completed 15-of-20 passes for 186 yards and two touchdowns, adding 50 rushing yards. 

Offense vs. defense: Tennessee averages only 249.3 total yards, including 159 net passing yards. Jackson’s 9.8 yards per attempt creates a large efficiency gap.  The Titans need sustained possessions and enough rushing success to avoid obvious passing downs. Baltimore’s injured centers and Jackson’s reported back issue deserve attention, especially when laying double digits after international travel.

2025 meeting: None; Baltimore won 24–16 in London in 2023. 

• Titans: RB Tyjae Spears—questionable, ankle. RB Tony Pollard returned to full practice after a foot issue. DL John Franklin-Myers—back, limited Thursday.  
• Ravens: EDGE Trey Hendrickson—out, fractured finger. C Ethan Pocic—knee and OL Jovaughn Gwyn—ankle, unavailable with significant injuries. OT Ronnie Stanley—toe, availability requires monitoring. Lamar Jackson returned to full practice Thursday after a back issue

Key ATS trend: Road team 5–0–1 ATS in the last six meetings.  

JACKSONVILLE JAGUARS (2–1) at CINCINNATI BENGALS (2–1)
1 p.m. ET, CBS | Line: Cincinnati -2½ | Total: 51½

Last games: Jacksonville crushed New England 35–6. Lawrence threw for 182 yards and three touchdowns, with one interception. Cincinnati lost 30–27 at Pittsburgh, despite Burrow completing 28-of-37 for 282 yards and three touchdowns without an interception.  

Offense vs. defense: Jacksonville’s improved rushing attack averages 119.3 yards per game. Cincinnati allows 355.7 total yards, including 260 passing yards, giving Lawrence an opportunity to build on his touchdown production.  

2025 meeting: Cincinnati won 31–27, covering -3½;   

• Jaguars: WR Jakobi Meyers—thumb, DT DaVon Hamilton—back, and OL Cole Van Lanen—knee, limited Thursday. CB Montaric Brown—hamstring, also limited. 
• Bengals: S Kyle Dugger—out, quadriceps. DT B.J. Hill—doubtful, Achilles. G Dalton Risner—knee, missed Thursday; S Jordan Battle—hamstring, S Bryan Cook—ankle, and CB DJ Turner—ankle, limited.

Key ATS trend: Cincinnati 6–1 ATS in its last seven after allowing more than 350 yards.  

MIAMI DOLPHINS (0–3) at MINNESOTA VIKINGS (3–0)
4:05 p.m. ET, FOX | Line: Minnesota -10½ | Total: 38½

Murray’s totals include a brief Week 1 appearance; last week was his first full game following his injury. 

Last games: Miami lost 24–10 to Kansas City. Willis threw for 210 yards and one interception, adding 56 rushing yards. Minnesota won 23–16 at Tampa Bay; Murray went 15-of-29 for 168 yards, one touchdown and one interception. 

Offense vs. defense: Minnesota holds opponents to 3.5 yards per rush, a difficult matchup for Miami after De’Von Achane’s season-ending ACL injury. Willis may need to create offense with his legs and quick throws. My assessment: Minnesota’s defense offers the clearest advantage, but covering 10½ also requires sufficient offensive production. Justin Jefferson’s uncertain ankle status matters considerably given Murray’s limited passing output. 

2025 meeting: None; Minnesota won 24–16 in 2022. 

Key Injuries:

• Dolphins: RB De’Von Achane—out for the season, torn ACL. RB Jaylen Wright—foot/stinger, returned to full practice Thursday. C Aaron Brewer—hand, limited Thursday. 
• Vikings: WR Justin Jefferson—out, ankle sprain. LB Blake Cashman—elbow, limited Thursday. 

Key ATS trend: Minnesota 7–0–1 ATS in its last eight overall. 

KANSAS CITY CHIEFS (3–0) at LAS VEGAS RAIDERS (3–0)
4:25 p.m. ET, CBS | Line: Kansas City -4½ | Total: 47½

Last games: Kansas City beat Miami 24–10. Mahomes completed 20-of-24 for 246 yards, two touchdowns and one interception. Las Vegas beat New Orleans 35–27; Cousins finished 22-of-33 for 248 yards and three touchdowns without an interception.  

Offense vs. defense: Kansas City averages 416.3 yards, including 153.3 rushing yards at 5.0 per carry. Las Vegas allows 4.5 yards per rush, suggesting the Chiefs can create favorable down-and-distance situations without relying entirely on Mahomes. Both teams average 29.3 points, and Las Vegas has allowed no fourth-quarter points.  

2025-season meetings: Kansas City won 31–0, covering -13½. Las Vegas won the January 4, 2026 rematch 14–12, covering +3½.  

Key Injuries:

• Chiefs: OT Josh Simmons—back, missed Wednesday and Thursday. CB L’Jarius Sneed—knee, limited. Patrick Mahomes, Rashee Rice and Chris Jones practiced fully despite appearing on the injury report.  
• Raiders: G Jackson Powers-Johnson—out, groin; Caleb Rogers is the expected replacement. RB Ashton Jeanty—ankle, practiced fully Thursday.  

Key ATS trend: Las Vegas 5–0 ATS in its last five against AFC opponents.  

LOS ANGELES CHARGERS (0–3) at SEATTLE SEAHAWKS (2–1)
4:25 p.m. ET, CBS | Line: Seattle -7 | Total: 42½

Darnold’s totals include a brief opening-game appearance; Drew Lock handled most of Seattle’s first two games. 

Last games: The Chargers lost 24–16 at Buffalo. Herbert threw for 226 yards, one touchdown and one interception. Seattle lost 33–31 at Washington, despite Darnold throwing for 379 yards and four touchdowns; his two interceptions were costly. 

Offense vs. defense: Seattle allows a league-low 228.7 yards per game and 4.0 yards per play, including only 141.7 net passing yards. That presents a major challenge for Herbert, whose completion rate is below 60%. Los Angeles needs its running game to keep Herbert out of repeated long-yardage situations. Seattle has demonstrated considerably more scoring potential through the air, but Darnold must reduce mistakes after a loss in which the offense produced enough points to win.

Key Injuries:

• Chargers: WR Ladd McConkey—foot, missed Thursday after being limited Wednesday. S Derwin James—hamstring/rest, did not practice. CB Donte Jackson—concussion, limited. TE Charlie Kolar—forearm and DL Dalvin Tomlinson—hamstring, missed practice. Final designations pending in the report reviewed.  
• Seahawks: RB Jadarian Price—chest, missed Thursday; RB George Holani—rib and S Julian Love—calf, limited. 

Key ATS trend: Underdog 7–0 ATS in the last seven meetings

DENVER BRONCOS (2–1) at SAN FRANCISCO 49ERS (3–0)
4:25 p.m. ET | Line: San Francisco -3 | Total: 47½

Last games: Denver beat the Rams 30–26. Nix completed only 17-of-34 for 186 yards but threw two touchdowns, with one interception. San Francisco beat Arizona 36–30; Purdy threw for 297 yards and four touchdowns without an interception.

Offense vs. defense: Purdy holds substantial advantages in accuracy, yards per attempt and touchdown-to-interception ratio. Denver averages only 275 offensive yards and 81 rushing yards, while San Francisco allows 5.0 yards per play and 3.7 per rush. 

• Broncos: RB J.K. Dobbins—hip, WR Jaylen Waddle—foot, and WR Marvin Mims Jr.—foot, practiced fully Thursday. EDGE Dondrea Tillman—hamstring, remained sidelined.
• 49ers: EDGE Nick Bosa is expected to miss another game with a calf injury. WR Mike Evans—ribs, availability uncertain. OT Trent Williams—neck, returned to limited practice; LB Dre Greenlaw—quadriceps, missed Thursday.

Key ATS trend: San Francisco 6–0 ATS in its last six after gaining more than 350 yards. 

DETROIT LIONS (2–1) at CAROLINA PANTHERS (1–2)
Sunday Night Football — 8:20 p.m. ET, NBC | Line: Detroit -3½ | Total: 50½

Last games: Detroit beat the Jets 31–24, with Goff completing 25-of-32 for 269 yards and two touchdowns without an interception. Carolina lost 21–18 at Cleveland; Young threw for 291 yards, one touchdown and one interception, completing only 26 of 48 attempts.

Offense vs. defense: Carolina allows a league-worst 193.3 rushing yards per game and 5.7 per carry. Detroit averages 120.7 rushing yards, giving it a clear opportunity to establish the run and create play-action openings. Goff’s eight touchdowns without an interception give Detroit the steadier current quarterback profile. Detroit won 42–24 in 2023.

Key Injuries:

• Lions: S Brian Branch remains unavailable on PUP while recovering from an Achilles injury. CB D.J. Reed—ribs, limited Thursday.  
• Panthers: WR Xavier Legette—out, knee; G Damien Lewis—out, elbow. WR Jalen Coker—questionable, quadriceps; OT Monroe Freeling—questionable, concussion; DTs Lee Hunter—foot and Cam Jackson—knee, questionable. 

ATS Key trend: Carolina 11–1 ATS in its last 12 following an ATS loss